ND Vaccine, inactivated (Strain rGM-Vll)

rGM-VII ND Vaccine Description

This inactivated Newcastle disease vaccine uses the rGM-VII strain, which is adapted for robust immune response in poultry. The vaccine:

• Provides strong humoral immunity
• Prevents outbreaks in commercial and backyard poultry
• Reduces morbidity, mortality, and production losses in flocks

Suitable for broilers, layers, and breeder chickens, the vaccine can be integrated into standard vaccination programs and combined with other routine immunizations (e.g., avian influenza, infectious bronchitis).

Immunization Program

• Chickens aged 0–14 days: Primary immunization
• Chickens aged over 60 days: Booster vaccination
• Hens before laying (14–21 days): Pre-lay booster

This schedule ensures optimal protection during critical growth and production periods.

Dosage & Administration

• Route:
  • Subcutaneous injection (neck)
  • Intramuscular injection

Dosage per bird:

• 0–14 days old: 0.2 mL
• Over 60 days old: 0.5 mL
• Hens 14–21 days before laying: 0.5 mL

Administration Notes:

• Use aseptic injection equipment
• Disinfect injection site
• Follow local immunization schedules for best results

Composition

• Inactivated Newcastle disease virus, strain rGM-VII
• Virus content before inactivation ≥ 10^8.5 EID₅₀/0.1 mL
• Uniform emulsion

Safety & Adverse Reactions

• Safe for healthy poultry
• No significant visible adverse reactions reported

Precautions

1. Vaccinate healthy chickens only
2. Do not freeze the vaccine; avoid high temperatures
3. Do not use if the vaccine shows:
   • Discoloration
   • Demulsification
   • Leakage
   • Foreign impurities
4. Bring to room temperature and shake well before use
5. Use the opened vaccine within 24 hours
6. Maintain aseptic injection procedures
7. Do not use within 28 days before slaughter
8. Dispose of used vaccine bottles, equipment, and residual vaccine safely

Packaging & Specification

• Specifications:
  • 250 mL/bottle
  • 500 mL/bottle
• Packaging:
  • 40 bottles/carton (250 mL)
  • 20 bottles/carton (500 mL)

Storage & Shelf Life

• Storage: 2–8°C, avoid freezing
• Shelf Life: 24 months